Lab test · Immunology
HLA-B27
Ankylosing spondylitis risk
- Blood sample
- No fasting
- Report within 4 days
- Home collection
What this test is for
Ankylosing spondylitis risk
HLA-B27 is a protein found on the surface of white blood cells in some people, and whether you have it is decided by your genes. It is strongly linked with ankylosing spondylitis, a type of inflammatory arthritis of the spine, and with related conditions such as reactive arthritis and some kinds of eye inflammation. The test helps your doctor judge how likely these conditions are, but it cannot diagnose them on its own.
Why a doctor may order it
- Long-term back pain and stiffness that is worse in the morning and eases with movement
- Back or buttock pain that started in a young adult
- Repeated episodes of a painful, red eye (uveitis)
- Joint pain and swelling after a gut or urinary infection
- A family history of ankylosing spondylitis
How to prepare
Fasting: Not needed.
Nothing special is needed before this test; you can eat, drink and take your usual medicines as normal. Because HLA-B27 is inherited and does not change, this test normally only needs to be done once.
At home
- Sample
- Blood sample
- How it works
- A trained sample collector comes to your home and draws a small amount of blood from a vein in your arm. It takes a few minutes, and you can move about normally straight after.
- Report
- Within 4 days of collection.
What the results can mean
The result is reported as positive or negative. A positive result makes ankylosing spondylitis or a related condition more likely when you have typical symptoms, but many people with HLA-B27 never develop any of these conditions. A negative result makes them less likely but does not rule them out. Your doctor will interpret the result with your symptoms, examination and scans.
What's included
One test: HLA-B27, from one blood sample.
Related tests
- C-Reactive Protein (CRP), QuantitativeC-reactive protein (CRP) is a protein made by the liver in response to inflammation.
- Rheumatoid Factor (RF)Rheumatoid arthritis check৳430
- Anti-CCP Antibodies (Anti-Cyclic Citrullinated Peptide)Rheumatoid arthritis check৳910
- Antinuclear Antibodies (ANA)Autoimmune disease screen (lupus)৳550
- Complement C3Immune system activity (lupus)৳750
Questions people ask
If I am HLA-B27 positive, will I get ankylosing spondylitis?
Most people who carry HLA-B27 never develop ankylosing spondylitis. The result only matters when it fits with symptoms and scan findings.
Does the HLA-B27 result change over time?
No. HLA-B27 is part of your genetic make-up, so the result stays the same for life and the test does not need repeating.
Can my children inherit HLA-B27?
Yes, it can be passed from parent to child. Carrying the marker does not mean a child will develop arthritis, so talk to your doctor before testing a child who has no symptoms.
How much does a HLA-B27 test cost in Dhaka?
With Mukti Health the price is ৳3,150, and the sample is collected at your home in Dhaka. You see the price again before you confirm the booking in the Mukti Health app.
Can I do the HLA-B27 test at home in Dhaka?
Yes. Book it in the Mukti Health app and a trained sample collector comes to your home in Dhaka to take the blood sample. You do not need to go to a laboratory.
How long does the HLA-B27 report take?
The report is usually ready within 4 days of the sample being collected.