Lab test · Hematology
G6PD (Quantitative)
Inherited enzyme deficiency (G6PD)
- Blood sample
- No fasting
- Report within 2 days
- Home collection
What this test is for
Inherited enzyme deficiency (G6PD)
G6PD (glucose-6-phosphate dehydrogenase) is an enzyme that protects red blood cells from damage. Some people inherit a low level of this enzyme, known as G6PD deficiency, which is more common in men. In these people, certain medicines, fava beans or infections can cause red cells to break down suddenly, leading to anaemia and jaundice. This test measures how much G6PD activity your red cells have.
Why a doctor may order it
- Jaundice or dark urine after certain medicines, fava beans or an infection
- Before medicines that can cause red cell breakdown in G6PD deficiency, such as primaquine for malaria
- Newborn jaundice that is severe or lasts longer than usual
- A family history of G6PD deficiency
- Unexplained anaemia due to red cell breakdown (haemolysis)
How to prepare
Fasting: Not needed.
You do not need to fast. If you have recently had an episode of red cell breakdown or a blood transfusion, tell your doctor, because the result can look falsely normal for a while afterwards and the test may need repeating a few months later.
At home
- Sample
- Blood sample
- How it works
- A trained collector takes a small blood sample from a vein in your arm at home, which takes a few minutes. If the test is for a baby or young child, mention this when you book.
- Report
- Within 2 days of collection.
What the results can mean
The report shows your G6PD activity compared with the laboratory's reference range. A low level suggests G6PD deficiency, which is lifelong but often causes no problems as long as known triggers are avoided. Women can have intermediate levels. Your doctor will interpret the result and, if you have the deficiency, can explain which medicines and foods to avoid.
What's included
One test: G6PD (Quantitative), from one blood sample.
Related tests
- Complete Blood Count (CBC)A complete blood count looks at the three main types of cells in your blood: red blood cells, which carry oxygen; white blood cells, which fight infection; and platelets, which help blood to clot.
- Reticulocyte CountReticulocytes are young red blood cells that have just been released from the bone marrow, and they mature into full red cells within a day or two.
- Peripheral Blood Film (PBF)In a peripheral blood film, a drop of your blood is spread thinly on a glass slide, stained and examined under a microscope.
- Serum Bilirubin (Total)Bilirubin is a yellow pigment made when old red blood cells are broken down.
- Direct Coombs Test (Direct Antiglobulin Test)Antibodies attacking red cells৳350
- Malaria Parasite (MP) Blood FilmThis test looks for malaria parasites in a drop of your blood that is spread on a glass slide, stained and examined under a microscope.
Questions people ask
What should people with G6PD deficiency avoid?
Common triggers include fava beans, mothballs containing naphthalene, and some medicines, including some antimalarials and certain antibiotics. Always tell your doctor and pharmacist that you have G6PD deficiency.
Why is G6PD deficiency more common in men?
The gene is carried on the X chromosome, so men with the gene are affected, while women are more often carriers, although some women are also affected.
Can the test be misleading after a haemolytic episode?
Yes. After red cells break down, the younger red cells that replace them have more of the enzyme, so the result can look normal. Your doctor may recommend repeating the test a few months later.
How much does a G6PD test cost in Dhaka?
With Mukti Health the price is ৳1,150, and the sample is collected at your home in Dhaka. You see the price again before you confirm the booking in the Mukti Health app.
Can I do the G6PD test at home in Dhaka?
Yes. Book it in the Mukti Health app and a trained sample collector comes to your home in Dhaka to take the blood sample. You do not need to go to a laboratory.
How long does the G6PD report take?
The report is usually ready within 2 days of the sample being collected.